Apply diclofenac gel or cream or spray twice daily to the ... Diclofenac may reduce the natriuretic (sodium-losing) effects of frusemide and thiazide diuretics and patients must be monitored ...

[20] The diclofenac epolamine TTS (1.3%) has been in use in Europe since 1993 and was approved by the US Food and Drug Administration in 2007 for treatment of pain due to minor sprains, strains ...