Speaking with her co-host Jamie-Lynn Sigler, who also has MS, on the latest episode of their MeSsy podcast, Applegate said, “I lay in bed screaming, like, the sharp pains, the ache, the squeezing.”

Christina Applegate is opening up about what she deals with during her struggles with the condition multiple sclerosis.

Christina Applegate will not suppress how difficult her battle with multiple sclerosis is. During the Monday, November 5, episode of her "MeSsy" podcast with Jamie-Lynn Sigler, who also has the medical condition,

In addition to the severity of her pain, Christina Applegate, also shared that she had started experiencing symptoms in areas she hadn’t previously

Christina Applegate share the reality of how hard it is living with multiple sclerosis (MS), including the severe pain. "I lay in bed screaming. Like, the sharp pains, the ache, the squeezing," said the Dead To Me actress during Tuesday's episode of her MeSsy podcast,

Christina Applegate has been open about her struggles with multiple sclerosis, getting down to the uncomfortable details of what it's like living with the chronic nervous system disease. The

Christina Applegate has shared the grueling effects of her battle with Multiple Sclerosis. The “Dead To Me” actress, who was diagnosed with MS in early 2021, has been open about how the condition — which affects the brain and nerves — has affected her daily life and Hollywood career.

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The "Married... with Children" alum also revealed that the disease has "traveled into my hands" and makes it difficult to pick up objects.