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大涨150%,RNA编辑疗法爆火
Wave公司开发的WVE-006是一种短的、化学修饰的寡核苷酸(AIMer),可以针对性地引导细胞内的腺苷脱氨酶(ADAR)对特定mRNA上的错配碱基进行精准编辑(A-to-I RNA编辑),进而纠正导致蛋白质功能失调的错误。
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